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Key Features of Humatrope 5mg / 15IU
- 15 IU / 5mg concentration per cartridge
- Recombinant human growth hormone (rHGH)
- Trusted pharmaceutical brand
- Long shelf life
- Secure packaging
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What is Humatrope 5mg / 15IU? It’s a synthetic growth hormone used in the treatment of growth hormone deficiency, Turner syndrome, and for muscle-wasting diseases. It helps boost metabolism, increase lean muscle mass, and improve recovery.
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Humatrope Composition and Features
Key Attributes
- Structure: Humatrope is a 191-amino acid polypeptide identical to the human growth hormone secreted by the pituitary gland.
- Molecular Weight: Approximately 22,125 daltons.
- Synthesis: Produced in a genetically modified strain of Escherichia coli carrying the human growth hormone gene.
Formulation
Humatrope is available as a sterile, white, lyophilized powder intended for subcutaneous or intramuscular administration after reconstitution.
Key Ingredients per Vial:
- 5 mg Somatropin (equivalent to 15 IU or 225 nanomoles)
- 25 mg Mannitol
- 5 mg Glycine
- 1.13 mg Dibasic Sodium Phosphate
Diluent: A 5 mL solution containing Water for Injection, 0.3% Metacresol (as a preservative), and 1.7% Glycerin.
Humatrope Indications and Usage
For Pediatric Patients
- Growth Hormone Deficiency: Treatment for children with inadequate secretion of growth hormone.
- Turner Syndrome: Addresses short stature in patients whose growth plates (epiphyses) are not closed.
- Idiopathic Short Stature: Helps children with unexplained short stature (height SDS ≤ -2.25).
- SHOX Deficiency: Indicated for children with short stature caused by mutations in the SHOX gene.
For Adult Patients
- Adult-Onset Growth Hormone Deficiency: Resulting from pituitary or hypothalamic disease, surgery, radiation therapy, or trauma.
- Childhood-Onset Growth Hormone Deficiency: Continuation of treatment for congenital, genetic, or acquired causes.
Note: Diagnosis confirmation often requires growth hormone stimulation tests.
Contraindications
- Allergies: Patients allergic to Metacresol or glycerin.
- Closed Epiphyses: Somatropin should not be used for growth promotion in children with closed growth plates.
- Active Malignancy: Somatropin is contraindicated in the presence of active cancer or tumors.
- Critical Illness: Not recommended for patients with acute conditions such as respiratory failure or post-surgical trauma.
- Prader-Willi Syndrome: Contraindicated in severely obese or respiratory-impaired patients without a diagnosis of growth hormone deficiency.
Warnings
- Diluent Sensitivity: Alternative diluents may be necessary for patients allergic to the supplied diluent.
- Storage: Reconstituted solutions must be refrigerated (2°–8°C) and used within the specified time.
- Risk of Respiratory Issues: Patients with Prader-Willi syndrome should be monitored for sleep apnea and respiratory infections.
- Mortality Risk: Increased mortality has been observed in critical illness cases when using somatropin.
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Humatrope 5mg / 15IU uses include growth hormone therapy for children and adults, muscle growth support, and anti-aging treatment plans. Athletes and bodybuilders often use it during cutting cycles.
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Get complete details from the Humatrope 5mg / 15IU wiki, or review our full product specs and guidelines on the official product page.
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